CECR2 MUTANT MICE AS A MODEL FOR HUMAN CAT EYE SYNDROME

Cecr2 mutant mice as a model for human cat eye syndrome

Abstract Cat eye syndrome (CES), a human genetic disorder caused by the inverted duplication of a region on chromosome 22, has been known since the late 1890s.Despite the significant impact this disorder has on affected individuals, models for CES have not been produced due to the difficulty of effectively duplicating 30hh bikini the corresponding

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Osthole Alleviates Neointimal Hyperplasia in Balloon-Induced Arterial Wall Injury by Suppressing Vascular Smooth Muscle Cell Proliferation and Downregulating Cyclin D1/CDK4 and Cyclin E1/CDK2 Expression

Percutaneous coronary intervention (PCI) is the most widely used therapy for treating ischemic heart disease.However, intimal hyperplasia and restenosis usually occur within months after angioplasty.Modern pharmacological researchers have proven that osthole, the major active coumarin of Cnidium monnieri (L.) Cusson, exerts potent antiproliferative

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Logistical management of iconic sporting events.

There are many potential complications and challenges involved in organizing iconic sporting events.Crowd numbers can be problematic, local weather can be random, and the host site may not be prepared to handle the supplementary demands that are faced.Logistics managers need to identify some of the coordination challenges of event planning such as

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